Scabies in the age of increasing drug resistance
Samar Khalil, Ossama Abbas, Abdul Ghani Kibbi, Mazen Kurban
What is scabies?
- Infestation of skin by human itch mite (Sarcoptes scabiei var. hominis)
Signs and Symptoms
- Pruritic, pimple like papular rash
- Rash can be tiny blisters vesicles and scales
- Scratching may lead to skin sores
- Sites like wrist, elbow, armpit, webbing between fingers, nipples, penis, waist, belt line, buttocks
How does one get scabies?
- Spreads by direct, prolong, skin to skin contact with infected person
- Frequently sexually acquired
- Can be spread indirectly, sharing clothes, towels, or bedding with infested person
How to diagnose scabies?
- Based on appearance and distribution of rash and presence of burrows
- Confirm by identifying mite, mite eggs, or mite fecal matter
- Scabiciides treat human scabies available with doctors prescription
To review mechanisms of resistance proposed in literature and potential solutions to this problem.
- Crotamiton, Precipitated sulfure, benzylbenozate, malathion
- Scabies is one of the W.H.O list of neglected diseases
- Resistance has increased throughout the years ,therefore newer methods of control needed
- 4 mechanisms with potential solutions to resistance
- More studies need to be done
- Years for vaccine to be available